Biochem/physiol Actions

Cell permeable: no

Primary TargetAcetylcholinesterase

Reversible: yes

Product competes with ATP.

General description

Cholinesterase antagonist. Antimyasthenic agent. Can partially reverse the effects of scopolamine-induced amnesia in rats.

A competitive and reversible inhibitor of acetylcholinesterase. Antimyasthenic agent. Can partially reverse the effects of scopolamine-induced amnesia in rats. Reported to improve learning and short-term memory in animal models.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Pilger, C., et al. 2001. J. Mol. Graph. Model19, 288.Iliev, A., et al. 1999. Methods Find. Exp. Clin. Pharmacol. 21, 297.Southan, G.J., et al. 1996. Br. J. Pharmacol.117, 619.Mutafova-Yambolieva, V.N., et al. 1993. Gen. Pharmacol. 24, 1253.

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Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Warning

Toxicity: Toxic (F)